Buy Ipamorelin Online
INN – developmental code name NNC 26-0161 is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue. It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1. Buy Ipamorelin Online
Ipamorelin significantly increases plasma growth hormone (GH) levels in both animals and humans.In addition, Ipamorelin stimulates body weight gain in animals. Like pralmorelin and GHRP-6, Ipamorelin does not affect prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or thyroid-stimulating hormone (TSH) levels.
However, unlike pralmorelin (GHRP-2) and GHRP-6, but similarly to growth hormone-releasing hormone (GHRH), Ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH.
Ipamorelin was originally developed by Novo Nordisk, and was investigated in phase II clinical trials by Helsinn Therapeutics for the treatment of postoperative ileus, but was discontinued due to lack of efficacy.
Ipamorelin has been used by athletes as a performance enhancing drug.
What is Ipamorelin?
With virtually no negative side effects, Ipamorelin is one of the safest, most effective forms of growth hormone (GH) restoration, widely used to support age management, disease management, sports performance and GH deficiency treatment protocols.
Ipamorelin is a pentapeptide, meaning that it is composed of five amino acids, that mimics the body’s natural GH release. Ipamorelin is a growth hormone releasing peptide (GHRP) and analogue of the hormone Ghrelin. It induces GH release and increases the number of somatarophs (cells responsible for GH release) in a GH pulse by suppressing somatostatin.
Ipamorelin is very similar to the growth hormone releasing peptides (GHRPs) GHRP 2 and GHRP 6 in that it mimics ghrelin (the hunger hormone) and targets a specific HGH pulse. However, with Ipamorelin unlike other GHRPs, this peptide doesn’t affect the release of cortisol, acetylcholine, prolactin and aldosterone thereby minimizing side effects experienced with other GH therapies, such as increased hunger.
Because there are virtually no negative side effects, Ipamorelin can be prescribed more aggressively and more frequently than other therapies without the risk of elevated cortisol and acetylcholine blood plasma levels. This helps optimize HGH levels for a longer period of time, leading to more successful health outcomes with Ipamorelin.
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